node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PTO0152 | PTO0429 | PTO0152 | PTO0429 | ATPases of the PP-loop superamily. | Hypothetical oxidoreductase. | 0.635 |
PTO0152 | PTO0521 | PTO0152 | PTO0521 | ATPases of the PP-loop superamily. | Molybdopterin biosynthesis MoeB protein. | 0.765 |
PTO0152 | thiI | PTO0152 | PTO0483 | ATPases of the PP-loop superamily. | Hypothetical thiamine biosynthesis protein thiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.924 |
PTO0152 | truA | PTO0152 | PTO0780 | ATPases of the PP-loop superamily. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. | 0.721 |
PTO0409 | thiI | PTO0409 | PTO0483 | Protein secretion chaperonin CsaA. | Hypothetical thiamine biosynthesis protein thiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.933 |
PTO0429 | PTO0152 | PTO0429 | PTO0152 | Hypothetical oxidoreductase. | ATPases of the PP-loop superamily. | 0.635 |
PTO0429 | thiI | PTO0429 | PTO0483 | Hypothetical oxidoreductase. | Hypothetical thiamine biosynthesis protein thiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.929 |
PTO0429 | truA | PTO0429 | PTO0780 | Hypothetical oxidoreductase. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. | 0.460 |
PTO0521 | PTO0152 | PTO0521 | PTO0152 | Molybdopterin biosynthesis MoeB protein. | ATPases of the PP-loop superamily. | 0.765 |
PTO0521 | PTO1061 | PTO0521 | PTO1061 | Molybdopterin biosynthesis MoeB protein. | Molybdenum cofactor biosynthesis protein C. | 0.747 |
PTO0521 | thiE | PTO0521 | PTO1288 | Molybdopterin biosynthesis MoeB protein. | Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.886 |
PTO0521 | thiI | PTO0521 | PTO0483 | Molybdopterin biosynthesis MoeB protein. | Hypothetical thiamine biosynthesis protein thiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.987 |
PTO0874 | thiI | PTO0874 | PTO0483 | methionyl-tRNA synthetase. | Hypothetical thiamine biosynthesis protein thiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.933 |
PTO1061 | PTO0521 | PTO1061 | PTO0521 | Molybdenum cofactor biosynthesis protein C. | Molybdopterin biosynthesis MoeB protein. | 0.747 |
PTO1061 | thiI | PTO1061 | PTO0483 | Molybdenum cofactor biosynthesis protein C. | Hypothetical thiamine biosynthesis protein thiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.990 |
PTO1061 | truA | PTO1061 | PTO0780 | Molybdenum cofactor biosynthesis protein C. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. | 0.582 |
ppa | thiI | PTO1354 | PTO0483 | Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. | Hypothetical thiamine biosynthesis protein thiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.917 |
ppa | valS | PTO1354 | PTO0532 | Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. | 0.410 |
thiE | PTO0521 | PTO1288 | PTO0521 | Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | Molybdopterin biosynthesis MoeB protein. | 0.886 |
thiE | thiI | PTO1288 | PTO0483 | Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | Hypothetical thiamine biosynthesis protein thiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.969 |