| node1 | node2 | node1 annotation | node2 annotation | score |
| PTO0170 | PTO0383 | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. | Beta-ketoacyl synthase; Thiolase. | 0.919 |
| PTO0170 | PTO0501 | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. | Acetyl-coenzyme A synthetase. | 0.699 |
| PTO0170 | PTO0502 | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. | Acetyl-coenzyme A synthetase. | 0.699 |
| PTO0170 | PTO0536 | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. | acyl-CoA synthetase. | 0.889 |
| PTO0170 | PTO0547 | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.910 |
| PTO0170 | PTO0999 | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. | 2-oxoglutarate synthase, beta chain. | 0.903 |
| PTO0170 | PTO1000 | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. | 2-oxoglutarate synthase, alpha chain. | 0.889 |
| PTO0170 | PTO1188 | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. | Beta-ketoacyl synthase; Thiolase. | 0.919 |
| PTO0170 | PTO1360 | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. | Pyruvate ferredoxin oxidoreductase, alpha chain. | 0.889 |
| PTO0170 | PTO1505 | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. | acetyl-CoA acetyltransferase. | 0.919 |
| PTO0383 | PTO0170 | Beta-ketoacyl synthase; Thiolase. | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. | 0.919 |
| PTO0383 | PTO0501 | Beta-ketoacyl synthase; Thiolase. | Acetyl-coenzyme A synthetase. | 0.770 |
| PTO0383 | PTO0502 | Beta-ketoacyl synthase; Thiolase. | Acetyl-coenzyme A synthetase. | 0.770 |
| PTO0383 | PTO0536 | Beta-ketoacyl synthase; Thiolase. | acyl-CoA synthetase. | 0.910 |
| PTO0383 | PTO0547 | Beta-ketoacyl synthase; Thiolase. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.914 |
| PTO0383 | PTO0999 | Beta-ketoacyl synthase; Thiolase. | 2-oxoglutarate synthase, beta chain. | 0.898 |
| PTO0383 | PTO1000 | Beta-ketoacyl synthase; Thiolase. | 2-oxoglutarate synthase, alpha chain. | 0.900 |
| PTO0383 | PTO1188 | Beta-ketoacyl synthase; Thiolase. | Beta-ketoacyl synthase; Thiolase. | 0.907 |
| PTO0383 | PTO1360 | Beta-ketoacyl synthase; Thiolase. | Pyruvate ferredoxin oxidoreductase, alpha chain. | 0.900 |
| PTO0383 | PTO1505 | Beta-ketoacyl synthase; Thiolase. | acetyl-CoA acetyltransferase. | 0.899 |