| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PTO0264 | PTO0546 | PTO0264 | PTO0546 | Mercuric reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Dihydrolipoamide dehydrogenase; E3 component of pyruvate complex; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.688 |
| PTO0264 | PTO0547 | PTO0264 | PTO0547 | Mercuric reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.992 |
| PTO0264 | PTO0548 | PTO0264 | PTO0548 | Mercuric reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Pyruvate dehydrogenase E1 component beta subunit. | 0.970 |
| PTO0264 | PTO0549 | PTO0264 | PTO0549 | Mercuric reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Pyruvate dehydrogenase E1 component alpha subunit. | 0.849 |
| PTO0264 | PTO0906 | PTO0264 | PTO0906 | Mercuric reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. | 0.805 |
| PTO0264 | PTO0996 | PTO0264 | PTO0996 | Mercuric reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Succinate dehydrogenase iron-sulfur protein. | 0.704 |
| PTO0264 | PTO1003 | PTO0264 | PTO1003 | Mercuric reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | succinyl-CoA synthetase beta chain. | 0.753 |
| PTO0264 | lipA | PTO0264 | PTO0550 | Mercuric reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.417 |
| PTO0264 | sucD | PTO0264 | PTO1002 | Mercuric reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.743 |
| PTO0546 | PTO0264 | PTO0546 | PTO0264 | Dihydrolipoamide dehydrogenase; E3 component of pyruvate complex; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Mercuric reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.688 |
| PTO0546 | PTO0547 | PTO0546 | PTO0547 | Dihydrolipoamide dehydrogenase; E3 component of pyruvate complex; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.999 |
| PTO0546 | PTO0548 | PTO0546 | PTO0548 | Dihydrolipoamide dehydrogenase; E3 component of pyruvate complex; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Pyruvate dehydrogenase E1 component beta subunit. | 0.999 |
| PTO0546 | PTO0549 | PTO0546 | PTO0549 | Dihydrolipoamide dehydrogenase; E3 component of pyruvate complex; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Pyruvate dehydrogenase E1 component alpha subunit. | 0.996 |
| PTO0546 | PTO0887 | PTO0546 | PTO0887 | Dihydrolipoamide dehydrogenase; E3 component of pyruvate complex; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Dihydrolipoamide dehydrogenase. | 0.904 |
| PTO0546 | PTO0906 | PTO0546 | PTO0906 | Dihydrolipoamide dehydrogenase; E3 component of pyruvate complex; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. | 0.805 |
| PTO0546 | PTO0996 | PTO0546 | PTO0996 | Dihydrolipoamide dehydrogenase; E3 component of pyruvate complex; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Succinate dehydrogenase iron-sulfur protein. | 0.704 |
| PTO0546 | PTO1003 | PTO0546 | PTO1003 | Dihydrolipoamide dehydrogenase; E3 component of pyruvate complex; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | succinyl-CoA synthetase beta chain. | 0.753 |
| PTO0546 | lipA | PTO0546 | PTO0550 | Dihydrolipoamide dehydrogenase; E3 component of pyruvate complex; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.951 |
| PTO0546 | sucD | PTO0546 | PTO1002 | Dihydrolipoamide dehydrogenase; E3 component of pyruvate complex; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.743 |
| PTO0547 | PTO0264 | PTO0547 | PTO0264 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Mercuric reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.992 |