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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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[Homology]
Score
PTO0549Pyruvate dehydrogenase E1 component alpha subunit. (333 aa)    
Predicted Functional Partners:
PTO0547
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.999
PTO0548
Pyruvate dehydrogenase E1 component beta subunit.
 0.999
PTO0546
Dihydrolipoamide dehydrogenase; E3 component of pyruvate complex; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
 0.996
PTO0887
Dihydrolipoamide dehydrogenase.
  
 
 0.955
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
     
 0.937
PTO1226
Glucose/mannose-6-phosphate isomerase.
    
 0.922
gdh2
Glucose-1-dehydrogenase; Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Is also significantly active with D- galactose as substrate, but not with D-xylose, L-arabinose, D-ribose, D-mannose, D-allose, D-glucosamine, 2-deoxy-D-glucose, or glucose-6- phosphate. Can utilize both NAD(+) and NADP(+) as electron acceptor, with a marked preference for NADP(+) (20-fold higher activity). Physiologically, may be involved in the degradation of both glucose and galactose through a non-phosphorylative variant of the Entner-Doudoroff pathway; Belongs to th [...]
  
 
 0.921
PTO0336
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.917
PTO0957
Malate oxidoreductase.
  
 
 0.916
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.914
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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