Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTO0631Long chain fatty acid CoA ligase. (557 aa)    
Predicted Functional Partners:
PTO0383
Beta-ketoacyl synthase; Thiolase.
  
 
 0.950
PTO0536
acyl-CoA synthetase.
    
 0.938
PTO1505
acetyl-CoA acetyltransferase.
  
 
 0.907
PTO0283
Acetyl-coenzyme A synthetase.
     
  0.873
PTO0170
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
  
 
 0.783
PTO0632
acyl-CoA transferases/carnitine dehydratase.
 
   
 0.778
PTO0169
2-methylcitrate-synthase.
  
 0.773
PTO0889
Citrate synthase.
  
 0.773
PTO0913
2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.720
PTO1466
2-isopropylmalate synthase.
  
 
 0.720
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
Server load: low (10%) [HD]