| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PTO0698 | PTO0699 | PTO0698 | PTO0699 | Putative CaaX prenyl protease 1. | Hypothetical protein. | 0.554 |
| PTO0698 | PTO0700 | PTO0698 | PTO0700 | Putative CaaX prenyl protease 1. | Hypothetical phosphoserine phosphatase. | 0.444 |
| PTO0698 | dnaJ | PTO0698 | PTO0841 | Putative CaaX prenyl protease 1. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.627 |
| PTO0698 | dnaK | PTO0698 | PTO0840 | Putative CaaX prenyl protease 1. | Chaperone protein Dank; Acts as a chaperone. | 0.575 |
| PTO0698 | grpE | PTO0698 | PTO0839 | Putative CaaX prenyl protease 1. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.633 |
| PTO0698 | htpX | PTO0698 | PTO0160 | Putative CaaX prenyl protease 1. | Protease HtpX; Belongs to the peptidase M48B family. | 0.711 |
| PTO0698 | infB | PTO0698 | PTO1284 | Putative CaaX prenyl protease 1. | Protein translation initiation factor 5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. | 0.409 |
| PTO0698 | nep1 | PTO0698 | PTO0697 | Putative CaaX prenyl protease 1. | Multicopy suppressor of ras1; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. | 0.678 |
| PTO0698 | purA | PTO0698 | PTO0194 | Putative CaaX prenyl protease 1. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.405 |
| PTO0699 | PTO0698 | PTO0699 | PTO0698 | Hypothetical protein. | Putative CaaX prenyl protease 1. | 0.554 |
| PTO0699 | PTO0700 | PTO0699 | PTO0700 | Hypothetical protein. | Hypothetical phosphoserine phosphatase. | 0.605 |
| PTO0699 | nep1 | PTO0699 | PTO0697 | Hypothetical protein. | Multicopy suppressor of ras1; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. | 0.492 |
| PTO0700 | PTO0698 | PTO0700 | PTO0698 | Hypothetical phosphoserine phosphatase. | Putative CaaX prenyl protease 1. | 0.444 |
| PTO0700 | PTO0699 | PTO0700 | PTO0699 | Hypothetical phosphoserine phosphatase. | Hypothetical protein. | 0.605 |
| dnaJ | PTO0698 | PTO0841 | PTO0698 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Putative CaaX prenyl protease 1. | 0.627 |
| dnaJ | dnaK | PTO0841 | PTO0840 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Chaperone protein Dank; Acts as a chaperone. | 0.999 |
| dnaJ | grpE | PTO0841 | PTO0839 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.999 |
| dnaJ | infB | PTO0841 | PTO1284 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Protein translation initiation factor 5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. | 0.899 |
| dnaJ | purA | PTO0841 | PTO0194 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.405 |
| dnaK | PTO0698 | PTO0840 | PTO0698 | Chaperone protein Dank; Acts as a chaperone. | Putative CaaX prenyl protease 1. | 0.575 |
