node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PTO0128 | PTO0673 | PTO0128 | PTO0673 | DNA polymerase delta catalytic subunit. | Replication factor A, large subunit. | 0.670 |
PTO0128 | PTO1245 | PTO0128 | PTO1245 | DNA polymerase delta catalytic subunit. | ATP-dependent DNA helicase. | 0.455 |
PTO0128 | PTO1419 | PTO0128 | PTO1419 | DNA polymerase delta catalytic subunit. | Replication factor-A protein 1. | 0.807 |
PTO0128 | dbh | PTO0128 | PTO1155 | DNA polymerase delta catalytic subunit. | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis. | 0.994 |
PTO0128 | fen | PTO0128 | PTO0228 | DNA polymerase delta catalytic subunit. | RAD-2/FEN-1 exonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathwa [...] | 0.987 |
PTO0128 | pcn | PTO0128 | PTO1316 | DNA polymerase delta catalytic subunit. | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.999 |
PTO0128 | radA | PTO0128 | PTO0741 | DNA polymerase delta catalytic subunit. | DNA repair and recombination protein radA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | 0.755 |
PTO0128 | secY | PTO0128 | PTO0663 | DNA polymerase delta catalytic subunit. | Protein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.542 |
PTO0673 | PTO0128 | PTO0673 | PTO0128 | Replication factor A, large subunit. | DNA polymerase delta catalytic subunit. | 0.670 |
PTO0673 | PTO1419 | PTO0673 | PTO1419 | Replication factor A, large subunit. | Replication factor-A protein 1. | 0.901 |
PTO0673 | dbh | PTO0673 | PTO1155 | Replication factor A, large subunit. | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis. | 0.470 |
PTO0673 | fen | PTO0673 | PTO0228 | Replication factor A, large subunit. | RAD-2/FEN-1 exonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathwa [...] | 0.635 |
PTO0673 | pcn | PTO0673 | PTO1316 | Replication factor A, large subunit. | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.856 |
PTO0673 | radA | PTO0673 | PTO0741 | Replication factor A, large subunit. | DNA repair and recombination protein radA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | 0.843 |
PTO1245 | PTO0128 | PTO1245 | PTO0128 | ATP-dependent DNA helicase. | DNA polymerase delta catalytic subunit. | 0.455 |
PTO1245 | PTO1419 | PTO1245 | PTO1419 | ATP-dependent DNA helicase. | Replication factor-A protein 1. | 0.516 |
PTO1245 | dbh | PTO1245 | PTO1155 | ATP-dependent DNA helicase. | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis. | 0.660 |
PTO1245 | fen | PTO1245 | PTO0228 | ATP-dependent DNA helicase. | RAD-2/FEN-1 exonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathwa [...] | 0.810 |
PTO1245 | pcn | PTO1245 | PTO1316 | ATP-dependent DNA helicase. | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.926 |
PTO1245 | radA | PTO1245 | PTO0741 | ATP-dependent DNA helicase. | DNA repair and recombination protein radA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | 0.847 |