| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PTO0158 | dnaJ | PTO0158 | PTO0841 | TPR-repeat-containing protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.711 |
| PTO0158 | dnaK | PTO0158 | PTO0840 | TPR-repeat-containing protein. | Chaperone protein Dank; Acts as a chaperone. | 0.879 |
| PTO0735 | PTO1195 | PTO0735 | PTO1195 | Thermosome subunit; Belongs to the TCP-1 chaperonin family. | Thermosome subunit; Belongs to the TCP-1 chaperonin family. | 0.999 |
| PTO0735 | dnaJ | PTO0735 | PTO0841 | Thermosome subunit; Belongs to the TCP-1 chaperonin family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.831 |
| PTO0735 | dnaK | PTO0735 | PTO0840 | Thermosome subunit; Belongs to the TCP-1 chaperonin family. | Chaperone protein Dank; Acts as a chaperone. | 0.938 |
| PTO0735 | grpE | PTO0735 | PTO0839 | Thermosome subunit; Belongs to the TCP-1 chaperonin family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.923 |
| PTO0735 | rpl10e | PTO0735 | PTO0715 | Thermosome subunit; Belongs to the TCP-1 chaperonin family. | 50S ribosomal protein L10e; Belongs to the universal ribosomal protein uL16 family. | 0.551 |
| PTO0735 | rpl13 | PTO0735 | PTO0323 | Thermosome subunit; Belongs to the TCP-1 chaperonin family. | Large subunit ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.601 |
| PTO0735 | rps2 | PTO0735 | PTO0517 | Thermosome subunit; Belongs to the TCP-1 chaperonin family. | Small subunit ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. | 0.643 |
| PTO0847 | dnaJ | PTO0847 | PTO0841 | Tetratricopeptide repeat family protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.711 |
| PTO0847 | dnaK | PTO0847 | PTO0840 | Tetratricopeptide repeat family protein. | Chaperone protein Dank; Acts as a chaperone. | 0.879 |
| PTO1142 | dnaJ | PTO1142 | PTO0841 | Hypothetical protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.711 |
| PTO1142 | dnaK | PTO1142 | PTO0840 | Hypothetical protein. | Chaperone protein Dank; Acts as a chaperone. | 0.879 |
| PTO1195 | PTO0735 | PTO1195 | PTO0735 | Thermosome subunit; Belongs to the TCP-1 chaperonin family. | Thermosome subunit; Belongs to the TCP-1 chaperonin family. | 0.999 |
| PTO1195 | dnaJ | PTO1195 | PTO0841 | Thermosome subunit; Belongs to the TCP-1 chaperonin family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.831 |
| PTO1195 | dnaK | PTO1195 | PTO0840 | Thermosome subunit; Belongs to the TCP-1 chaperonin family. | Chaperone protein Dank; Acts as a chaperone. | 0.938 |
| PTO1195 | grpE | PTO1195 | PTO0839 | Thermosome subunit; Belongs to the TCP-1 chaperonin family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.923 |
| PTO1195 | rpl10e | PTO1195 | PTO0715 | Thermosome subunit; Belongs to the TCP-1 chaperonin family. | 50S ribosomal protein L10e; Belongs to the universal ribosomal protein uL16 family. | 0.581 |
| PTO1195 | rpl13 | PTO1195 | PTO0323 | Thermosome subunit; Belongs to the TCP-1 chaperonin family. | Large subunit ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.611 |
| PTO1195 | rps2 | PTO1195 | PTO0517 | Thermosome subunit; Belongs to the TCP-1 chaperonin family. | Small subunit ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. | 0.647 |
STRING v12.5 is now available!
