| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PTO0258 | PTO0259 | PTO0258 | PTO0259 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| PTO0258 | PTO0391 | PTO0258 | PTO0391 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA-Polymerase subunit P. | 0.975 |
| PTO0258 | PTO0866 | PTO0258 | PTO0866 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit E'. | 0.978 |
| PTO0258 | rpoH | PTO0258 | PTO0260 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | 0.998 |
| PTO0258 | spt4 | PTO0258 | PTO0867 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit E; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. | 0.859 |
| PTO0258 | spt5 | PTO0258 | PTO0445 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Hypothetical transcription antitermination protein NusG; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. | 0.934 |
| PTO0259 | PTO0258 | PTO0259 | PTO0258 | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| PTO0259 | PTO0391 | PTO0259 | PTO0391 | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA-Polymerase subunit P. | 0.983 |
| PTO0259 | PTO0866 | PTO0259 | PTO0866 | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit E'. | 0.980 |
| PTO0259 | rpoH | PTO0259 | PTO0260 | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | 0.999 |
| PTO0259 | spt4 | PTO0259 | PTO0867 | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit E; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. | 0.884 |
| PTO0259 | spt5 | PTO0259 | PTO0445 | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Hypothetical transcription antitermination protein NusG; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. | 0.987 |
| PTO0374 | PTO0866 | PTO0374 | PTO0866 | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the C-terminal section; belongs to the protein kinase superfamily. Tyr prot [...] | DNA-directed RNA polymerase subunit E'. | 0.993 |
| PTO0374 | PTO0868 | PTO0374 | PTO0868 | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the C-terminal section; belongs to the protein kinase superfamily. Tyr prot [...] | Archaeal conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | 0.992 |
| PTO0374 | rps24e | PTO0374 | PTO0869 | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the C-terminal section; belongs to the protein kinase superfamily. Tyr prot [...] | Small subunit ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family. | 0.996 |
| PTO0374 | rps27ae | PTO0374 | PTO0870 | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the C-terminal section; belongs to the protein kinase superfamily. Tyr prot [...] | Small subunit ribosomal protein S27AE; Belongs to the eukaryotic ribosomal protein eS31 family. | 0.992 |
| PTO0374 | spt4 | PTO0374 | PTO0867 | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the C-terminal section; belongs to the protein kinase superfamily. Tyr prot [...] | DNA-directed RNA polymerase subunit E; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. | 0.992 |
| PTO0374 | spt5 | PTO0374 | PTO0445 | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the C-terminal section; belongs to the protein kinase superfamily. Tyr prot [...] | Hypothetical transcription antitermination protein NusG; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. | 0.763 |
| PTO0391 | PTO0258 | PTO0391 | PTO0258 | DNA-directed RNA-Polymerase subunit P. | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.975 |
| PTO0391 | PTO0259 | PTO0391 | PTO0259 | DNA-directed RNA-Polymerase subunit P. | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.983 |
