STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTO0887Dihydrolipoamide dehydrogenase. (446 aa)    
Predicted Functional Partners:
PTO0547
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 0.999
PTO0548
Pyruvate dehydrogenase E1 component beta subunit.
  
 0.995
PTO0503
Aminomethyltransferase.
  
 0.966
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.965
PTO1170
Decarboxylating glycine dehydrogenase.
  
 
 0.957
PTO0549
Pyruvate dehydrogenase E1 component alpha subunit.
  
 
 0.955
PTO1171
Decarboxylating glycine dehydrogenase.
  
 0.937
PTO0533
Glutamine synthetase.
  
 
 0.908
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.908
PTO0858
Serine hydroxymethyltransferase.
  
 
 0.908
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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