Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PTO09132-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (386 aa)    
Predicted Functional Partners:
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.993
PTO0910
3-isopropylmalate dehydrogenase.
 0.992
leuD
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.
 
 
 0.988
PTO1464
3-isopropylmalate dehydratase large subunit.
 
 
 0.961
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 
 0.940
PTO1465
3-isopropylmalate dehydratase.
  
 
 0.936
PTO0383
Beta-ketoacyl synthase; Thiolase.
  
 
 0.912
PTO1505
acetyl-CoA acetyltransferase.
  
 
 0.912
PTO0536
acyl-CoA synthetase.
    
 0.881
PTO1075
Acetolactate synthase large subunit.
  
 
 0.865
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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