| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PTO0497 | PTO0958 | PTO0497 | PTO0958 | Archaeal kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. | Hypothetical conserved protein DUF52; Belongs to the MEMO1 family. | 0.684 |
| PTO0497 | eno | PTO0497 | PTO1234 | Archaeal kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.684 |
| PTO0497 | fni | PTO0497 | PTO0496 | Archaeal kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. | Hypothetical isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.995 |
| PTO0497 | rpl13 | PTO0497 | PTO0323 | Archaeal kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. | Large subunit ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.684 |
| PTO0497 | rpoK | PTO0497 | PTO0543 | Archaeal kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. | DNA-directed RNA polymerase subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. | 0.684 |
| PTO0497 | rpoN | PTO0497 | PTO0325 | Archaeal kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. | DNA-directed RNA polymerase subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. | 0.684 |
| PTO0497 | rps2 | PTO0497 | PTO0517 | Archaeal kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. | Small subunit ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. | 0.684 |
| PTO0497 | rps9 | PTO0497 | PTO0324 | Archaeal kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. | Small subunit ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. | 0.684 |
| PTO0955 | PTO0958 | PTO0955 | PTO0958 | Conserved hypothetical protein DUF51. | Hypothetical conserved protein DUF52; Belongs to the MEMO1 family. | 0.995 |
| PTO0955 | PTO0959 | PTO0955 | PTO0959 | Conserved hypothetical protein DUF51. | Pyruvate formate-lyase activating enzyme. | 0.971 |
| PTO0958 | PTO0497 | PTO0958 | PTO0497 | Hypothetical conserved protein DUF52; Belongs to the MEMO1 family. | Archaeal kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. | 0.684 |
| PTO0958 | PTO0955 | PTO0958 | PTO0955 | Hypothetical conserved protein DUF52; Belongs to the MEMO1 family. | Conserved hypothetical protein DUF51. | 0.995 |
| PTO0958 | PTO0959 | PTO0958 | PTO0959 | Hypothetical conserved protein DUF52; Belongs to the MEMO1 family. | Pyruvate formate-lyase activating enzyme. | 0.988 |
| PTO0958 | eno | PTO0958 | PTO1234 | Hypothetical conserved protein DUF52; Belongs to the MEMO1 family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.696 |
| PTO0958 | fni | PTO0958 | PTO0496 | Hypothetical conserved protein DUF52; Belongs to the MEMO1 family. | Hypothetical isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.712 |
| PTO0958 | rpl13 | PTO0958 | PTO0323 | Hypothetical conserved protein DUF52; Belongs to the MEMO1 family. | Large subunit ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.688 |
| PTO0958 | rpoK | PTO0958 | PTO0543 | Hypothetical conserved protein DUF52; Belongs to the MEMO1 family. | DNA-directed RNA polymerase subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. | 0.684 |
| PTO0958 | rpoN | PTO0958 | PTO0325 | Hypothetical conserved protein DUF52; Belongs to the MEMO1 family. | DNA-directed RNA polymerase subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. | 0.684 |
| PTO0958 | rps2 | PTO0958 | PTO0517 | Hypothetical conserved protein DUF52; Belongs to the MEMO1 family. | Small subunit ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. | 0.699 |
| PTO0958 | rps9 | PTO0958 | PTO0324 | Hypothetical conserved protein DUF52; Belongs to the MEMO1 family. | Small subunit ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. | 0.699 |