Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. (324 aa)    
Predicted Functional Partners:
PTO0169
2-methylcitrate-synthase.
  
 0.992
PTO0889
Citrate synthase.
  
 0.992
PTO0935
Aconitate hydratase.
  
 0.980
PTO0995
Succinate dehydrogenase flavoprotein subunit.
  
 0.966
PTO0957
Malate oxidoreductase.
  
 0.963
PTO1109
Aspartate aminotransferase.
  
 0.962
PTO0996
Succinate dehydrogenase iron-sulfur protein.
  
 0.954
PTO0427
Fumarate hydratase.
    
 0.953
PTO0336
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.945
PTO0168
Isocitrate dehydrogenase [NADP].
  
 0.941
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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