STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTO09992-oxoglutarate synthase, beta chain. (306 aa)    
Predicted Functional Partners:
PTO1000
2-oxoglutarate synthase, alpha chain.
 
 0.999
PTO1360
Pyruvate ferredoxin oxidoreductase, alpha chain.
 0.995
PTO1003
succinyl-CoA synthetase beta chain.
    
 0.975
sucD
succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.974
PTO0168
Isocitrate dehydrogenase [NADP].
    
 0.948
PTO0536
acyl-CoA synthetase.
    
 0.922
PTO1315
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.918
PTO0336
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.915
PTO0547
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 
 0.912
PTO1226
Glucose/mannose-6-phosphate isomerase.
    
 0.912
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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