Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
PTO10002-oxoglutarate synthase, alpha chain. (631 aa)    
Predicted Functional Partners:
PTO0999
2-oxoglutarate synthase, beta chain.
 
 0.999
PTO1361
Pyruvate ferredoxin oxidoreductase, beta chain.
 
 0.995
sucD
succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.950
PTO1003
succinyl-CoA synthetase beta chain.
    
 0.950
PTO0536
acyl-CoA synthetase.
  
 0.936
PTO1315
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.920
PTO0549
Pyruvate dehydrogenase E1 component alpha subunit.
    
 0.912
PTO1226
Glucose/mannose-6-phosphate isomerase.
    
 0.912
PTO0336
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.911
PTO0548
Pyruvate dehydrogenase E1 component beta subunit.
  
 
 0.910
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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