Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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sucDsuccinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (284 aa)    
Predicted Functional Partners:
PTO1003
succinyl-CoA synthetase beta chain.
 0.999
PTO0995
Succinate dehydrogenase flavoprotein subunit.
 
 0.994
PTO0996
Succinate dehydrogenase iron-sulfur protein.
 0.993
PTO0547
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.989
PTO0999
2-oxoglutarate synthase, beta chain.
  
 
 0.974
PTO0910
3-isopropylmalate dehydrogenase.
  
 0.965
PTO1000
2-oxoglutarate synthase, alpha chain.
    
 0.950
PTO0270
methylmalonyl-CoA mutase alpha subunit.
    
 0.927
PTO0170
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
  
 0.925
PTO1361
Pyruvate ferredoxin oxidoreductase, beta chain.
  
 
 0.924
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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