Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PTO1004Nicotinate phosphoribosyltransferase. (385 aa)    
Predicted Functional Partners:
PTO0671
Isochorismatase.
 
 
 0.952
PTO0129
Nicotinamide-nucleotide adenylyltransferase.
    
 0.940
nadE
NAD synthase related protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
 
 
 0.806
PTO0942
5'-methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage.
    
 0.788
surE
Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.769
PTO1003
succinyl-CoA synthetase beta chain.
   
 
 0.624
PTO0222
Predicted nucleotide-utilizing enzyme; Similar to molybdopterin-biosynthesis enzyme MoeA.
  
 
 0.622
PTO0232
Pantothenate kinase.
    
 0.619
PTO0963
MutT/NUCliX family hydrolase.
    
 0.610
nadK
ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
  
 0.564
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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