STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTO10262-keto-3-deoxy gluconate aldolase. (287 aa)    
Predicted Functional Partners:
gad
Gluconate/galactonate dehydratase; Involved in the degradation of glucose and galactose via the nonphosphorylative variant of Entner-Doudoroff pathway. Catalyzes the dehydration of gluconate to produce 2-keto-3-deoxygluconate (KDG). It is also able to catalyze the dehydration of galactonate to produce 2- keto-3-deoxygalactonate (KDGal); Belongs to the mandelate racemase/muconate lactonizing enzyme family. GaD subfamily.
 
  
 0.935
PTO0332
Succinate-semialdehyde dehydrogenase [NADP+]; NADP-dependent dehydrogenase of the nED (non-phosphorylated Entner-Doudoroff) pathway with highest activity towards glyceraldehydes (e.g. D,L-glyceraldehyde and D-glyceraldehyde), to a lesser extent towards D,L-glyceraldehyde-3-phosphate and glycolaldehyde, but no activity towards aliphatic or aromatic aldehydes.
  
 
 0.927
PTO1279
Dihydrodipicolinate synthase; Involved in the degradation of glucose via the Entner- Doudoroff pathway. Catalyzes the reversible cleavage of 2-keto-3-deoxy- 6-phosphogluconate (KDPG) and 2-keto-3-deoxygluconate (KDG) forming pyruvate and glyceraldehyde 3-phosphate or glyceraldehyde, respectively. It is also able to catalyze the reversible cleavage of 2- keto-3-deoxy-6-phosphogalactonate (KDPGal) and 2-keto-3- deoxygalactonate (KDGal). It is equally active with both D- and L- glyceraldehyde; Belongs to the DapA family. KDPG aldolase subfamily.
  
  
 
0.924
PTO0675
Transcriptional repressor/ROK family.
  
 
 0.884
PTO1216
Glucokinase.
  
 
 0.884
PTO0348
Triosephosphate isomerase; Belongs to the HisA/HisF family.
  
 
 0.858
PTO0845
Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
  
 
 0.851
PTO0148
Mannonate dehydratase.
 
 
 0.846
PTO0336
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.844
PTO1166
Phosphoglucomutase/phosphomannomutase; Belongs to the phosphohexose mutase family.
    
 0.842
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.