Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
PTO1236Hypothetical protein. (137 aa)    
Predicted Functional Partners:
PTO0374
O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the C-terminal section; belongs to the protein kinase superfamily. Tyr prot [...]
    
 0.999
PTO1007
Hypothetical protein.
     
 0.858
PTO1235
ATP-dependent protease La; Belongs to the peptidase S16 family.
       0.852
rps17e
Small subunit ribosomal protein S17E; Belongs to the eukaryotic ribosomal protein eS17 family.
       0.550
hel308
Helicase involved in UV-protection; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
       0.550
PTO0589
Xanthine-guanine phosphoribosyltransferase.
       0.518
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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