Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTO1279Dihydrodipicolinate synthase; Involved in the degradation of glucose via the Entner- Doudoroff pathway. Catalyzes the reversible cleavage of 2-keto-3-deoxy- 6-phosphogluconate (KDPG) and 2-keto-3-deoxygluconate (KDG) forming pyruvate and glyceraldehyde 3-phosphate or glyceraldehyde, respectively. It is also able to catalyze the reversible cleavage of 2- keto-3-deoxy-6-phosphogalactonate (KDPGal) and 2-keto-3- deoxygalactonate (KDGal). It is equally active with both D- and L- glyceraldehyde; Belongs to the DapA family. KDPG aldolase subfamily. (266 aa)    
Predicted Functional Partners:
PTO1367
Aspartate-semialdehyde dehydrogenase.
 
 
 0.944
PTO1417
Homoserine dehydrogenase.
 
 
 0.915
gad
Gluconate/galactonate dehydratase; Involved in the degradation of glucose and galactose via the nonphosphorylative variant of Entner-Doudoroff pathway. Catalyzes the dehydration of gluconate to produce 2-keto-3-deoxygluconate (KDG). It is also able to catalyze the dehydration of galactonate to produce 2- keto-3-deoxygalactonate (KDGal); Belongs to the mandelate racemase/muconate lactonizing enzyme family. GaD subfamily.
 
 
 0.883
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
 
  
 0.860
PTO1368
Aspartokinase.
 
 
 0.850
PTO1026
2-keto-3-deoxy gluconate aldolase.
  
  
 
0.842
rps17e
Small subunit ribosomal protein S17E; Belongs to the eukaryotic ribosomal protein eS17 family.
  
    0.841
PTO0332
Succinate-semialdehyde dehydrogenase [NADP+]; NADP-dependent dehydrogenase of the nED (non-phosphorylated Entner-Doudoroff) pathway with highest activity towards glyceraldehydes (e.g. D,L-glyceraldehyde and D-glyceraldehyde), to a lesser extent towards D,L-glyceraldehyde-3-phosphate and glycolaldehyde, but no activity towards aliphatic or aromatic aldehydes.
  
 
 0.827
PTO0348
Triosephosphate isomerase; Belongs to the HisA/HisF family.
  
 
 0.767
PTO0336
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.755
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.