Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PTO1349Signal sequence processing protein Sec11 precursor. (269 aa)    
Predicted Functional Partners:
PTO0924
Signal peptidase I.
     
  0.757
lig
DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
   
 0.694
polB
DNA polymerase II small subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family.
       0.684
srp54
Signal recognition particle protein Srp54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
  
 0.676
PTO0943
mRNA 3'-end processing factor; Contains metallo-lactamase domain 295; Sua5 superfamily-related protein.
   
 
  0.672
PTO1348
Hypothetical membrane associated protein.
       0.668
hel308
Helicase involved in UV-protection; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
     
  0.635
PTO1350
Transporter.
       0.615
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
    0.575
PTO1347
L-fuculose phosphate aldolase.
  
    0.568
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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