Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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PTO1356Diphosphomevalonate decarboxylase; Catalyzes the phosphorylation of mevalonate (MVA) to yield mevalonate-3-phosphate. Functions in an alternative mevalonate pathway, which passes through mevalonate 3-phosphate rather than mevalonate 5- phosphate. Also able to catalyze the formation of isobutene via the conversion of 3-hydroxyisovalerate (3-HIV) to an unstable 3-phosphate intermediate that undergoes a spontaneous decarboxylation. (324 aa)    
Predicted Functional Partners:
PTO0479
Hypothetical phosphoglycerate kinase.
  
  
 0.975
PTO1143
3-hydroxy-3-methylglutaryl-coenzyme A reductase.
  
 
 0.933
PTO0497
Archaeal kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids.
     
 0.706
atpC
A1AO H+ ATPase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
   0.698
PTO1357
Hypothetical protein.
       0.682
PTO1199
Octaprenyl-diphosphate synthase; Farnesyl pyrophosphate synthetase/ geranyltransferase/farnesyltransferase/hexaprenyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
 
 0.668
PTO1344
Permease.
  
     0.666
PTO0384
3-hydroxy-3-methylglutaryl-CoA-synthase/3- oxoacyl-[acyl-carrier-protein] synthase III; Belongs to the thiolase-like superfamily. UPF0219 family.
  
 
 0.659
PTO0848
Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
 
 0.655
PTO0985
Hypothetical membrane protein; Involved in the biosynthesis of polysaccharides.
  
     0.655
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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