| node1 | node2 | node1 annotation | node2 annotation | score |
| PTO0219 | PTO1428 | GTPase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | Transporter, MMPL family. | 0.443 |
| PTO0818 | PTO1428 | Hypothetical protein. | Transporter, MMPL family. | 0.472 |
| PTO0985 | PTO1356 | Hypothetical membrane protein; Involved in the biosynthesis of polysaccharides. | Diphosphomevalonate decarboxylase; Catalyzes the phosphorylation of mevalonate (MVA) to yield mevalonate-3-phosphate. Functions in an alternative mevalonate pathway, which passes through mevalonate 3-phosphate rather than mevalonate 5- phosphate. Also able to catalyze the formation of isobutene via the conversion of 3-hydroxyisovalerate (3-HIV) to an unstable 3-phosphate intermediate that undergoes a spontaneous decarboxylation. | 0.655 |
| PTO0985 | PTO1428 | Hypothetical membrane protein; Involved in the biosynthesis of polysaccharides. | Transporter, MMPL family. | 0.400 |
| PTO1356 | PTO0985 | Diphosphomevalonate decarboxylase; Catalyzes the phosphorylation of mevalonate (MVA) to yield mevalonate-3-phosphate. Functions in an alternative mevalonate pathway, which passes through mevalonate 3-phosphate rather than mevalonate 5- phosphate. Also able to catalyze the formation of isobutene via the conversion of 3-hydroxyisovalerate (3-HIV) to an unstable 3-phosphate intermediate that undergoes a spontaneous decarboxylation. | Hypothetical membrane protein; Involved in the biosynthesis of polysaccharides. | 0.655 |
| PTO1356 | PTO1428 | Diphosphomevalonate decarboxylase; Catalyzes the phosphorylation of mevalonate (MVA) to yield mevalonate-3-phosphate. Functions in an alternative mevalonate pathway, which passes through mevalonate 3-phosphate rather than mevalonate 5- phosphate. Also able to catalyze the formation of isobutene via the conversion of 3-hydroxyisovalerate (3-HIV) to an unstable 3-phosphate intermediate that undergoes a spontaneous decarboxylation. | Transporter, MMPL family. | 0.448 |
| PTO1427 | PTO1428 | Hypothetical protein. | Transporter, MMPL family. | 0.693 |
| PTO1427 | PTO1429 | Hypothetical protein. | O6-methylguanine-DNA methyltransferase/endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA (By similarity); In the N-terminal section; belongs to the MGMT family. | 0.519 |
| PTO1428 | PTO0219 | Transporter, MMPL family. | GTPase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | 0.443 |
| PTO1428 | PTO0818 | Transporter, MMPL family. | Hypothetical protein. | 0.472 |
| PTO1428 | PTO0985 | Transporter, MMPL family. | Hypothetical membrane protein; Involved in the biosynthesis of polysaccharides. | 0.400 |
| PTO1428 | PTO1356 | Transporter, MMPL family. | Diphosphomevalonate decarboxylase; Catalyzes the phosphorylation of mevalonate (MVA) to yield mevalonate-3-phosphate. Functions in an alternative mevalonate pathway, which passes through mevalonate 3-phosphate rather than mevalonate 5- phosphate. Also able to catalyze the formation of isobutene via the conversion of 3-hydroxyisovalerate (3-HIV) to an unstable 3-phosphate intermediate that undergoes a spontaneous decarboxylation. | 0.448 |
| PTO1428 | PTO1427 | Transporter, MMPL family. | Hypothetical protein. | 0.693 |
| PTO1428 | PTO1429 | Transporter, MMPL family. | O6-methylguanine-DNA methyltransferase/endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA (By similarity); In the N-terminal section; belongs to the MGMT family. | 0.554 |
| PTO1428 | PTO1430 | Transporter, MMPL family. | Hypothetical protein. | 0.429 |
| PTO1429 | PTO1427 | O6-methylguanine-DNA methyltransferase/endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA (By similarity); In the N-terminal section; belongs to the MGMT family. | Hypothetical protein. | 0.519 |
| PTO1429 | PTO1428 | O6-methylguanine-DNA methyltransferase/endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA (By similarity); In the N-terminal section; belongs to the MGMT family. | Transporter, MMPL family. | 0.554 |
| PTO1429 | PTO1430 | O6-methylguanine-DNA methyltransferase/endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA (By similarity); In the N-terminal section; belongs to the MGMT family. | Hypothetical protein. | 0.584 |
| PTO1430 | PTO1428 | Hypothetical protein. | Transporter, MMPL family. | 0.429 |
| PTO1430 | PTO1429 | Hypothetical protein. | O6-methylguanine-DNA methyltransferase/endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA (By similarity); In the N-terminal section; belongs to the MGMT family. | 0.584 |