Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PTO1445Hypothetical protein. (171 aa)    
Predicted Functional Partners:
cobS
Cobalamin [5'-phosphate] synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
    
  0.949
cobD
Cobalmin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
    
  0.949
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
       0.773
prf1
Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
       0.572
PTO0124
Hypothetical protein.
       0.550
PTO0212
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Belongs to the UPF0284 family.
       0.550
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
       0.550
PTO1047
Glutamine-hydrolyzing asparagine synthase.
       0.540
gck
Glycerate kinase, putative; Catalyzes the ATP-dependent phosphorylation of D-glycerate to 2-phosphoglycerate. It can also partially utilize GTP, CTP or UTP as phosphate donor.
       0.455
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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