STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
PTO1505acetyl-CoA acetyltransferase. (388 aa)    
Predicted Functional Partners:
PTO1504
3-hydroxybutyryl-CoA dehydrogenase.
 
 0.997
PTO0384
3-hydroxy-3-methylglutaryl-CoA-synthase/3- oxoacyl-[acyl-carrier-protein] synthase III; Belongs to the thiolase-like superfamily. UPF0219 family.
  
 0.985
PTO1021
3-hydroxybutyryl-CoA dehydrogenase/3-hydroxybutyryl-CoA dehydratase.
  
 0.972
PTO0954
enoyl-CoA hydratase/isomerase family.
  
 0.947
sucD
succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.923
PTO0170
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
  
 
 0.919
PTO1143
3-hydroxy-3-methylglutaryl-coenzyme A reductase.
 
  
 0.919
PTO1003
succinyl-CoA synthetase beta chain.
  
 
 0.915
PTO0283
Acetyl-coenzyme A synthetase.
  
 
 0.914
PTO0547
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 
 0.914
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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