node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SJZ44225.1 | SJZ88954.1 | SAMN02745116_00316 | SAMN02745116_01739 | tRNA threonylcarbamoyl adenosine modification protein YeaZ. | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | 0.981 |
SJZ44225.1 | tsaD | SAMN02745116_00316 | SAMN02745116_00319 | tRNA threonylcarbamoyl adenosine modification protein YeaZ. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.996 |
SJZ78135.1 | SJZ88954.1 | SAMN02745116_01421 | SAMN02745116_01739 | Surface polysaccharide O-acyltransferase, integral membrane enzyme. | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | 0.646 |
SJZ87646.1 | SJZ88954.1 | SAMN02745116_01689 | SAMN02745116_01739 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | 0.711 |
SJZ88954.1 | SJZ44225.1 | SAMN02745116_01739 | SAMN02745116_00316 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | tRNA threonylcarbamoyl adenosine modification protein YeaZ. | 0.981 |
SJZ88954.1 | SJZ78135.1 | SAMN02745116_01739 | SAMN02745116_01421 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | Surface polysaccharide O-acyltransferase, integral membrane enzyme. | 0.646 |
SJZ88954.1 | SJZ87646.1 | SAMN02745116_01739 | SAMN02745116_01689 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.711 |
SJZ88954.1 | SJZ88978.1 | SAMN02745116_01739 | SAMN02745116_01740 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | Protein N-acetyltransferase, RimJ/RimL family. | 0.697 |
SJZ88954.1 | SJZ94220.1 | SAMN02745116_01739 | SAMN02745116_01904 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | Protein of unknown function. | 0.493 |
SJZ88954.1 | SJZ95794.1 | SAMN02745116_01739 | SAMN02745116_01954 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | 0.488 |
SJZ88954.1 | glmU | SAMN02745116_01739 | SAMN02745116_00821 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.495 |
SJZ88954.1 | smpB | SAMN02745116_01739 | SAMN02745116_00308 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.515 |
SJZ88954.1 | trmD | SAMN02745116_01739 | SAMN02745116_02301 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | tRNA (guanine37-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.641 |
SJZ88954.1 | tsaD | SAMN02745116_01739 | SAMN02745116_00319 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.977 |
SJZ88978.1 | SJZ88954.1 | SAMN02745116_01740 | SAMN02745116_01739 | Protein N-acetyltransferase, RimJ/RimL family. | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | 0.697 |
SJZ94220.1 | SJZ88954.1 | SAMN02745116_01904 | SAMN02745116_01739 | Protein of unknown function. | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | 0.493 |
SJZ95794.1 | SJZ88954.1 | SAMN02745116_01954 | SAMN02745116_01739 | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | 0.488 |
SJZ95794.1 | smpB | SAMN02745116_01954 | SAMN02745116_00308 | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.524 |
glmU | SJZ88954.1 | SAMN02745116_00821 | SAMN02745116_01739 | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | 0.495 |
smpB | SJZ88954.1 | SAMN02745116_00308 | SAMN02745116_01739 | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | 0.515 |