STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metAAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (308 aa)    
Predicted Functional Partners:
SJZ69132.1
Aspartate kinase; Belongs to the aspartokinase family.
 
 0.962
SKA01062.1
Homoserine dehydrogenase.
  
 
 0.942
SKA01195.1
5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family.
  
  
 0.927
SKA01176.1
Cystathionine gamma-synthase.
 
 
 0.923
SKA01476.1
Cystathionine beta-lyase.
  
 
 0.911
trpB
Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
    
  0.891
ilvA
L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 
 0.876
SJZ37596.1
L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.868
SJZ37586.1
L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.866
SJZ68901.1
5-methyltetrahydrofolate--homocysteine methyltransferase.
  
  
 0.802
Your Current Organism:
Pilibacter termitis
NCBI taxonomy Id: 263852
Other names: CCUG 49613, P. termitis, Pilibacter termitis Higashiguchi et al. 2006, gut bacterium 1 of Coptotermes formosanus, strain TI-1
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