STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folE2GTP cyclohydrolase I; Converts GTP to 7,8-dihydroneopterin triphosphate. (270 aa)    
Predicted Functional Partners:
AAZ61212.1
Putative 6-pyruvoyl tetrahydrobiopterin synthase protein.
    
 0.930
AAZ63029.1
GTP cyclohydrolase I.
     
 0.922
AAZ59823.1
Dihydroneopterin triphosphate pyrophosphatase.
  
  
  0.916
ribB
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
 0.907
AAZ60902.1
3,4-dihydroxy-2-butanone 4-phosphate synthase; In the N-terminal section; belongs to the DHBP synthase family.
    
 0.907
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.
     
 0.904
moaA
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
    
  0.900
AAZ64834.1
Twin-arginine translocation pathway signal.
     
  0.900
AAZ59940.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.812
AAZ62654.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.812
Your Current Organism:
Cupriavidus pinatubonensis
NCBI taxonomy Id: 264198
Other names: C. pinatubonensis JMP134, Cupriavidus necator JMP134, Cupriavidus pinatubonensis JMP134, Ralstonia eutropha JMP134, Ralstonia eutropha str. JMP134, Ralstonia eutropha strain JMP134, Ralstonia sp. JMP134, Wautersia eutropha JMP134
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.