| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dacB | grpE | stu0116 | stu0119 | D-alanyl-D-alanine-carboxypeptidase. | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.515 |
| dacB | hrcA | stu0116 | stu0118 | D-alanyl-D-alanine-carboxypeptidase. | Heat shock protein, transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.515 |
| dacB | mur3 | stu0116 | stu0117 | D-alanyl-D-alanine-carboxypeptidase. | Peptidoglycan hydrolase. | 0.808 |
| dacB | stu0114 | stu0116 | stu0114 | D-alanyl-D-alanine-carboxypeptidase. | Phosphoglycerate mutase, truncated; Truncated. | 0.526 |
| dacB | stu0115 | stu0116 | stu0115 | D-alanyl-D-alanine-carboxypeptidase. | Phosphoglycerate mutase, truncated; Truncated. | 0.799 |
| dnaK | grpE | stu0120 | stu0119 | Heat shock protein, chaperonin; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.999 |
| dnaK | hrcA | stu0120 | stu0118 | Heat shock protein, chaperonin; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Heat shock protein, transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.988 |
| dnaK | stu0115 | stu0120 | stu0115 | Heat shock protein, chaperonin; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Phosphoglycerate mutase, truncated; Truncated. | 0.405 |
| grpE | dacB | stu0119 | stu0116 | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | D-alanyl-D-alanine-carboxypeptidase. | 0.515 |
| grpE | dnaK | stu0119 | stu0120 | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | Heat shock protein, chaperonin; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
| grpE | hrcA | stu0119 | stu0118 | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | Heat shock protein, transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.994 |
| grpE | mur3 | stu0119 | stu0117 | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | Peptidoglycan hydrolase. | 0.515 |
| grpE | stu0115 | stu0119 | stu0115 | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | Phosphoglycerate mutase, truncated; Truncated. | 0.510 |
| hrcA | dacB | stu0118 | stu0116 | Heat shock protein, transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | D-alanyl-D-alanine-carboxypeptidase. | 0.515 |
| hrcA | dnaK | stu0118 | stu0120 | Heat shock protein, transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | Heat shock protein, chaperonin; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.988 |
| hrcA | grpE | stu0118 | stu0119 | Heat shock protein, transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.994 |
| hrcA | mur3 | stu0118 | stu0117 | Heat shock protein, transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | Peptidoglycan hydrolase. | 0.515 |
| hrcA | stu0115 | stu0118 | stu0115 | Heat shock protein, transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | Phosphoglycerate mutase, truncated; Truncated. | 0.471 |
| mur3 | dacB | stu0117 | stu0116 | Peptidoglycan hydrolase. | D-alanyl-D-alanine-carboxypeptidase. | 0.808 |
| mur3 | grpE | stu0117 | stu0119 | Peptidoglycan hydrolase. | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.515 |