STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adcRZinc transport transcriptional repressor. (151 aa)    
Predicted Functional Partners:
adcB
Zinc (Zn2+) ABC uptake transporter membrane-spanning protein.
  
  
 0.993
adcC
Zinc (Zn2+) ABC uptake transporter ATP-binding protein.
  
  
 0.978
adcA
Zinc (Zn2+) ABC uptake transporter substrate binding protein; Belongs to the bacterial solute-binding protein 9 family.
  
  
 0.929
birA
biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.614
stu1602
Conserved hypothetical protein.
  
     0.608
dnaD
DNA replication protein dnaD.
  
     0.606
rgpF
Polysaccharide biosynthesis protein.
  
     0.603
nrdR
Conserved hypothetical protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
      
 0.594
stu0183
Conserved hypothetical protein, putative protein kinase.
   
   0.575
mntH
Metal ion (Mn2+-iron) transporter (Nramp) family protein; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.
      
 0.566
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.