Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
adcRZinc transport transcriptional repressor. (151 aa)    
Predicted Functional Partners:
adcC
Zinc (Zn2+) ABC uptake transporter ATP-binding protein.
  
  
 0.999
adcB
Zinc (Zn2+) ABC uptake transporter membrane-spanning protein.
  
  
 0.999
adcA
Zinc (Zn2+) ABC uptake transporter substrate binding protein; Belongs to the bacterial solute-binding protein 9 family.
  
  
 0.998
copY
Negative transcriptional regulator - copper transport operon.
     
 0.855
stu0932
Cation diffusion facilitor (CDF) family protein.
  
  
 0.662
argR
Arginine repressor; Regulates arginine biosynthesis genes.
      
 0.644
nrdR
Conserved hypothetical protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
      
 0.617
stu1602
Conserved hypothetical protein.
  
     0.608
dnaD
DNA replication protein dnaD.
  
     0.606
rgpF
Polysaccharide biosynthesis protein.
  
     0.603
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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