Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pepCCysteine aminopeptidase C; Belongs to the peptidase C1 family. (445 aa)    
Predicted Functional Partners:
pepO
Endopeptidase O.
  
   
 0.805
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
     
 0.722
pepXP
X-prolyl dipeptidyl peptidase; Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline; Belongs to the peptidase S15 family.
  
   
 0.697
pncB
Nicotinate phosphoribosyltransferase, putative; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
       0.694
pepN
Lysyl-aminopeptidase, aminopeptidase N.
  
 
 0.679
stu0158
Polar amino acid ABC uptake transporter ATP-binding protein.
      
 0.647
pepT
Tripeptidase; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
      
 0.583
stu0228
Conserved hypothetical, predicted membrane protein (TMS3).
       0.523
pepP
Aminopeptidase P; XAA-pro aminopeptidase; Belongs to the peptidase M24B family.
     
 0.508
stu0225
acyl-CoA thioesterase 1, truncated; Truncated.
 
     0.468
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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