Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ureIUrea channel. (171 aa)    
Predicted Functional Partners:
ureD
Urease accessory protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
   
 0.931
ureC
Urea amidohydrolase (urease) alpha subunit; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
     
 0.914
ureE
Urease accessory protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
   
 0.899
ureF
Urease accessory protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
   
 0.845
ureG
Urease accessory protein; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
     
 0.722
ureA
Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family.
       0.712
ureB
Urea amidohydrolase (urease) beta subunit; Belongs to the urease beta subunit family.
     
 0.709
stu0043
Hypothetical protein.
  
     0.610
stu0289
ABC transporter membrane-spanning protein.
 
     0.470
cbiM
Cobalamin biosynthesis protein, putative transporter.
 
     0.466
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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