STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metNPolar amino acid ABC uptake transporter ATP binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (355 aa)    
Predicted Functional Partners:
stu0302
ABC transporter membrane-spanning protein.
 
 0.999
stu0297
ABC transporter substrate binding protein; Belongs to the nlpA lipoprotein family.
 
 0.995
stu1633
Conserved hypothetical protein, putative lipoprotein; Belongs to the nlpA lipoprotein family.
 
 0.993
stu0176
Oligopeptide ABC uptake transporter ATP binding protein, truncated; Truncated.
     
0.862
metF
5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
   
  
 0.850
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.840
stu0300
Succinyl-diaminopimelic descuccinlyasadipeptidase, truncated; Truncated.
     
 0.795
cmhR
Probable metCcysK operon transcriptional activator; Belongs to the LysR transcriptional regulatory family.
   
 
 0.777
stu1411
ABC transporter, truncated; Truncated.
 
     
0.673
metE
5-methyl tetrahydropteroyltriglutamate -- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
  
 0.645
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
Server load: low (18%) [HD]