STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
manLMannose PTS system component IIAB. (330 aa)    
Predicted Functional Partners:
manN
Mannose PTS system component IID.
 
 0.999
manM
Mannose PTS system component IIC.
 
 0.999
ptsH
Phosphocarrier protein HPr (histidine-containing protein).
  
 0.999
stu0330
Conserved hypothetical protein.
 
 
 0.994
stu1358
Mannose-6-phosphate isomerase, truncated; Truncated.
 
  
 0.945
stu1359
Mannose-6-phosphate isomerase, truncated; Truncated.
    
 0.931
pmi1
Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family.
    
 0.931
scrK
Fructokinase.
    
 0.867
ptsI
Phosphoenolpyruvate:sugar phosphotransferase system enzyme I; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
  
  
 0.854
stu0401
Fructose PTS system component IIABC, truncated; Truncated.
  
  
 0.741
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.