| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| guaB | purC | stu2016 | stu0030 | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Phosphoribosylaminoimidazole - succinocarboxamide synthase (SAICAR synthetase). | 0.675 |
| guaB | purD | stu2016 | stu0040 | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Phosphoribosylamine-glycine ligase (GAR synthetase); Belongs to the GARS family. | 0.724 |
| guaB | purE | stu2016 | stu0041 | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Phosphoribosylaminoimidazole carboxylase I (AIR carboxylase, catalytic subunit); Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.808 |
| guaB | purK | stu2016 | stu0042 | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Phosphoribosylaminoimidazole carboxylase II (AIR carboxylase); Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.692 |
| guaB | purL | stu2016 | stu0031 | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Phosphoribosylformylglycinamidine synthase II (FGAM synthetase). | 0.880 |
| guaB | purM | stu2016 | stu0033 | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Phosphoribosylformylglycinamide cyclo-ligase (AIR synthetase). | 0.853 |
| guaB | pyrP | stu2016 | stu0524 | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Uracil permease. | 0.405 |
| guaB | stu0336 | stu2016 | stu0336 | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Conserved hypothetical, predicted membrane protein (TMS13). | 0.493 |
| purC | guaB | stu0030 | stu2016 | Phosphoribosylaminoimidazole - succinocarboxamide synthase (SAICAR synthetase). | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.675 |
| purC | purD | stu0030 | stu0040 | Phosphoribosylaminoimidazole - succinocarboxamide synthase (SAICAR synthetase). | Phosphoribosylamine-glycine ligase (GAR synthetase); Belongs to the GARS family. | 0.959 |
| purC | purE | stu0030 | stu0041 | Phosphoribosylaminoimidazole - succinocarboxamide synthase (SAICAR synthetase). | Phosphoribosylaminoimidazole carboxylase I (AIR carboxylase, catalytic subunit); Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.997 |
| purC | purK | stu0030 | stu0042 | Phosphoribosylaminoimidazole - succinocarboxamide synthase (SAICAR synthetase). | Phosphoribosylaminoimidazole carboxylase II (AIR carboxylase); Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.995 |
| purC | purL | stu0030 | stu0031 | Phosphoribosylaminoimidazole - succinocarboxamide synthase (SAICAR synthetase). | Phosphoribosylformylglycinamidine synthase II (FGAM synthetase). | 0.999 |
| purC | purM | stu0030 | stu0033 | Phosphoribosylaminoimidazole - succinocarboxamide synthase (SAICAR synthetase). | Phosphoribosylformylglycinamide cyclo-ligase (AIR synthetase). | 0.974 |
| purC | stu0336 | stu0030 | stu0336 | Phosphoribosylaminoimidazole - succinocarboxamide synthase (SAICAR synthetase). | Conserved hypothetical, predicted membrane protein (TMS13). | 0.496 |
| purD | guaB | stu0040 | stu2016 | Phosphoribosylamine-glycine ligase (GAR synthetase); Belongs to the GARS family. | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.724 |
| purD | purC | stu0040 | stu0030 | Phosphoribosylamine-glycine ligase (GAR synthetase); Belongs to the GARS family. | Phosphoribosylaminoimidazole - succinocarboxamide synthase (SAICAR synthetase). | 0.959 |
| purD | purE | stu0040 | stu0041 | Phosphoribosylamine-glycine ligase (GAR synthetase); Belongs to the GARS family. | Phosphoribosylaminoimidazole carboxylase I (AIR carboxylase, catalytic subunit); Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.998 |
| purD | purK | stu0040 | stu0042 | Phosphoribosylamine-glycine ligase (GAR synthetase); Belongs to the GARS family. | Phosphoribosylaminoimidazole carboxylase II (AIR carboxylase); Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.984 |
| purD | purL | stu0040 | stu0031 | Phosphoribosylamine-glycine ligase (GAR synthetase); Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase II (FGAM synthetase). | 0.999 |