Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
comFALate competence protein required for DNA uptake. (439 aa)    
Predicted Functional Partners:
comFC
Late competence protein.
  
  
 0.992
comGA
Late competence protein, ABC transporter subunit.
   
  
 0.989
comEA
Late competence protein required for DNA binding and uptake.
   
  
 0.972
comEC
Late competence protein required for DNA uptake.
   
  
 0.943
comGC
Late competence protein, exogenous DNA-binding protein.
 
  
 0.933
dprA
DNA processing protein, Smf family.
   
  
 0.919
ssbB
Single strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
  
 0.907
endA
Competence associated membrane nuclease.
      
 0.852
coiA
Competence protein, transcription factor.
   
  
 0.844
radC
DNA repair protein; Belongs to the UPF0758 family.
      
 0.838
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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