STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nifS2Aminotransferase (class V), putative. (381 aa)    
Predicted Functional Partners:
thiI
Thiamine biosynthesis protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
 0.988
nifU
Conserved hypothetical protein, NifU family protein.
 
 0.955
stu0545
Molybdopterin biosynthesis protein (HesA/MoeB/ThiF family protein), putative.
   
 0.951
nifS3
Aminotransferase (class V), putative.
  
  
 
0.916
stu1846
Transcriptional regulator, putative; Belongs to the sulfur carrier protein TusA family.
   
 
 0.754
stu1366
Conserved hypothetical protein, Rrf2 family protein.
  
  
 0.630
stu0410
Unknown protein.
       0.596
pps
Non-ribosomal peptide synthetase.
  
 
 0.573
dnaK
Heat shock protein, chaperonin; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
  
 0.543
acpP1
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
    
 
 0.530
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.