STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadRTranscriptional regulator. (368 aa)    
Predicted Functional Partners:
stu1858
Conserved hypothetical protein.
   
    0.965
stu1435
Transcriptional regulator, GntR family, putative.
   
    0.929
stu1893
Trehalose operon transcriptional regulator GntR family, truncated; Truncated.
  
    0.665
stu0428
MutT/nudix family protein.
     
 0.623
stu0887
Transcription regulator GntR family.
   
    0.619
stu1892
Trehalose operon transcriptional repressor GntR family, truncated; Truncated.
   
    0.619
stu0701
Conserved hypothetical, predicted membrane protein (TMS6).
 
     0.545
pncB
Nicotinate phosphoribosyltransferase, putative; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
     
 0.525
fur
Ferric transport regulator protein; Belongs to the Fur family.
  
    0.520
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
     
 0.491
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.