Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gdhANADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (456 aa)    
Predicted Functional Partners:
gnlA
Glutamine synthetase.
  
 
 0.992
acoL
Acetoin/pyruvate dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase.
  
 
 0.945
stu0462
Conserved hypothetical protein.
  
 
 0.935
gshAB
Conserved hypothetical protein; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine.
    
 0.928
argJ
Ornithine acetyltransferase / amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
     
 0.925
aspC2
Aspartate aminotransferase, putative.
  
 
 0.912
gltA
Citrate synthase; Belongs to the citrate synthase family.
   
 0.897
glr
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
  
 
 0.890
amtB
Ammonium uptake transporter.
  
  
 0.888
icd
Isocitrate dehydrogenase.
   
 0.881
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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