| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| hk08 | idi | stu1421 | stu0562 | Sensor histidine kinase (homolog to HK03 Spn). | Isopentenyl diphosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.406 |
| hk08 | mvaD | stu1421 | stu0560 | Sensor histidine kinase (homolog to HK03 Spn). | Mevalonate pyrophosphate decarboxylase. | 0.406 |
| hk08 | mvaK1 | stu1421 | stu0559 | Sensor histidine kinase (homolog to HK03 Spn). | Mevalonate kinase. | 0.406 |
| hk08 | mvaK2 | stu1421 | stu0561 | Sensor histidine kinase (homolog to HK03 Spn). | Phosphomevalonate kinase. | 0.406 |
| idi | hk08 | stu0562 | stu1421 | Isopentenyl diphosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Sensor histidine kinase (homolog to HK03 Spn). | 0.406 |
| idi | ispA | stu0562 | stu1216 | Isopentenyl diphosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Geranyltranstransferase, farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.950 |
| idi | mvaA | stu0562 | stu0576 | Isopentenyl diphosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. | 0.914 |
| idi | mvaD | stu0562 | stu0560 | Isopentenyl diphosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Mevalonate pyrophosphate decarboxylase. | 0.997 |
| idi | mvaK1 | stu0562 | stu0559 | Isopentenyl diphosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Mevalonate kinase. | 0.977 |
| idi | mvaK2 | stu0562 | stu0561 | Isopentenyl diphosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Phosphomevalonate kinase. | 0.975 |
| idi | mvaS | stu0562 | stu0577 | Isopentenyl diphosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | hydroxymethylglutaryl-CoA synthase (HMG-CoA synthase). | 0.952 |
| idi | stu1667 | stu0562 | stu1667 | Isopentenyl diphosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Conserved hypothetical protein. | 0.412 |
| ispA | idi | stu1216 | stu0562 | Geranyltranstransferase, farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Isopentenyl diphosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.950 |
| ispA | mvaA | stu1216 | stu0576 | Geranyltranstransferase, farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. | 0.797 |
| ispA | mvaD | stu1216 | stu0560 | Geranyltranstransferase, farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Mevalonate pyrophosphate decarboxylase. | 0.952 |
| ispA | mvaK1 | stu1216 | stu0559 | Geranyltranstransferase, farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Mevalonate kinase. | 0.410 |
| ispA | mvaS | stu1216 | stu0577 | Geranyltranstransferase, farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | hydroxymethylglutaryl-CoA synthase (HMG-CoA synthase). | 0.786 |
| mvaA | idi | stu0576 | stu0562 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. | Isopentenyl diphosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.914 |
| mvaA | ispA | stu0576 | stu1216 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. | Geranyltranstransferase, farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.797 |
| mvaA | mvaD | stu0576 | stu0560 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. | Mevalonate pyrophosphate decarboxylase. | 0.925 |