STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mvaDMevalonate pyrophosphate decarboxylase. (314 aa)    
Predicted Functional Partners:
mvaK2
Phosphomevalonate kinase.
 
 
 0.998
idi
Isopentenyl diphosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.992
mvaK1
Mevalonate kinase.
 
  
 0.984
ispA
Geranyltranstransferase, farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 0.947
mvaS
hydroxymethylglutaryl-CoA synthase (HMG-CoA synthase).
 
 
 0.928
mvaA
3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
 
  
 0.854
lysS
lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
      0.583
stu0558
Conserved hypothetical protein.
       0.442
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.