Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hdhLL-2-hydroxyisocaproate dehydrogenase; Belongs to the LDH/MDH superfamily. (316 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.967
acoB
Acetoin dehydrogenase complex, E1 component, beta subunit.
  
 0.954
pfl
Pyruvate formate-lyase.
   
 
 0.947
acoA
Acetoin dehydrogenase complex, E1 component, alpha subunit.
   
 
 0.922
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
  
 
0.919
pgi
Glucose-6-phosphate isomerase.
  
 0.895
gapN
NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.883
aspC2
Aspartate aminotransferase, putative.
  
 0.882
als
Acetolactate synthase; Belongs to the TPP enzyme family.
  
 0.864
ilvB
Acetolactate synthase, large subunit.
  
 0.864
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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