| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aroD | coaA | stu0638 | stu0799 | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | Pantothenate kinase. | 0.517 |
| aroD | dgk | stu0638 | stu0618 | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | Diacylglycerol kinase. | 0.614 |
| aroD | eetB | stu0638 | stu0650 | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | Exfoliative exotoxin B, putative. | 0.576 |
| aroD | ftsL | stu0638 | stu1702 | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | Cell division protein; Essential cell division protein; Belongs to the FtsL family. | 0.497 |
| aroD | idi | stu0638 | stu0562 | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | Isopentenyl diphosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.525 |
| aroD | ppnK | stu0638 | stu1457 | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.574 |
| aroD | rplC | stu0638 | stu1934 | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.624 |
| aroD | rpsB | stu0638 | stu0073 | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.592 |
| coaA | aroD | stu0799 | stu0638 | Pantothenate kinase. | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.517 |
| coaA | dgk | stu0799 | stu0618 | Pantothenate kinase. | Diacylglycerol kinase. | 0.607 |
| coaA | eetB | stu0799 | stu0650 | Pantothenate kinase. | Exfoliative exotoxin B, putative. | 0.575 |
| coaA | ftsL | stu0799 | stu1702 | Pantothenate kinase. | Cell division protein; Essential cell division protein; Belongs to the FtsL family. | 0.487 |
| coaA | idi | stu0799 | stu0562 | Pantothenate kinase. | Isopentenyl diphosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.620 |
| coaA | ppnK | stu0799 | stu1457 | Pantothenate kinase. | ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.572 |
| coaA | rplC | stu0799 | stu1934 | Pantothenate kinase. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.571 |
| dgk | aroD | stu0618 | stu0638 | Diacylglycerol kinase. | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.614 |
| dgk | coaA | stu0618 | stu0799 | Diacylglycerol kinase. | Pantothenate kinase. | 0.607 |
| dgk | eetB | stu0618 | stu0650 | Diacylglycerol kinase. | Exfoliative exotoxin B, putative. | 0.622 |
| dgk | ftsL | stu0618 | stu1702 | Diacylglycerol kinase. | Cell division protein; Essential cell division protein; Belongs to the FtsL family. | 0.573 |
| dgk | idi | stu0618 | stu0562 | Diacylglycerol kinase. | Isopentenyl diphosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.585 |