| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| clpL | dnaJ | stu1614 | stu0121 | ATP-dependent proteinase ATP-binding subunit; Belongs to the ClpA/ClpB family. | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | 0.872 |
| clpL | dnaK | stu1614 | stu0120 | ATP-dependent proteinase ATP-binding subunit; Belongs to the ClpA/ClpB family. | Heat shock protein, chaperonin; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.939 |
| clpL | grpE | stu1614 | stu0119 | ATP-dependent proteinase ATP-binding subunit; Belongs to the ClpA/ClpB family. | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.830 |
| clpL | hrcA | stu1614 | stu0118 | ATP-dependent proteinase ATP-binding subunit; Belongs to the ClpA/ClpB family. | Heat shock protein, transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.614 |
| clpL | htpX | stu1614 | stu0715 | ATP-dependent proteinase ATP-binding subunit; Belongs to the ClpA/ClpB family. | Heat shock protein, putative protease; Belongs to the peptidase M48B family. | 0.552 |
| cspB | dnaJ | stu0838 | stu0121 | Cold shock protein B. | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | 0.678 |
| cspB | dnaK | stu0838 | stu0120 | Cold shock protein B. | Heat shock protein, chaperonin; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.753 |
| cspB | grpE | stu0838 | stu0119 | Cold shock protein B. | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.611 |
| cspB | hrcA | stu0838 | stu0118 | Cold shock protein B. | Heat shock protein, transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.440 |
| cspB | htpX | stu0838 | stu0715 | Cold shock protein B. | Heat shock protein, putative protease; Belongs to the peptidase M48B family. | 0.525 |
| dnaJ | clpL | stu0121 | stu1614 | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | ATP-dependent proteinase ATP-binding subunit; Belongs to the ClpA/ClpB family. | 0.872 |
| dnaJ | cspB | stu0121 | stu0838 | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | Cold shock protein B. | 0.678 |
| dnaJ | dnaK | stu0121 | stu0120 | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | Heat shock protein, chaperonin; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
| dnaJ | ftsH | stu0121 | stu0012 | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.721 |
| dnaJ | grpE | stu0121 | stu0119 | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.997 |
| dnaJ | hrcA | stu0121 | stu0118 | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | Heat shock protein, transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.953 |
| dnaJ | htpX | stu0121 | stu0715 | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | Heat shock protein, putative protease; Belongs to the peptidase M48B family. | 0.589 |
| dnaJ | msrA1 | stu0121 | stu1343 | Heat shock protein, chaperonin; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.695 |
| dnaK | clpL | stu0120 | stu1614 | Heat shock protein, chaperonin; Acts as a chaperone; Belongs to the heat shock protein 70 family. | ATP-dependent proteinase ATP-binding subunit; Belongs to the ClpA/ClpB family. | 0.939 |
| dnaK | cspB | stu0120 | stu0838 | Heat shock protein, chaperonin; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Cold shock protein B. | 0.753 |
