Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pilDPrepilin peptidase type IV. (215 aa)    
Predicted Functional Partners:
comGA
Late competence protein, ABC transporter subunit.
 
 
 0.923
comGB
Late competence protein, ABC transporter subunit.
 
  
 0.907
comEC
Late competence protein required for DNA uptake.
 
  
 0.868
comEA
Late competence protein required for DNA binding and uptake.
   
  
 0.749
dprA
DNA processing protein, Smf family.
  
  
 0.740
comGC
Late competence protein, exogenous DNA-binding protein.
  
  
 0.736
dpr
Peroxide resistance protein,non-heme iron-containing ferritin; Belongs to the Dps family.
       0.727
stu1860
Competence protein, putative.
  
  
 0.663
cinA
Competence/damage inducible protein; Belongs to the CinA family.
     
 0.651
comFA
Late competence protein required for DNA uptake.
   
  
 0.641
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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