Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
copBCu2+-Cu+-Ag+-P-type ATPase. (735 aa)    
Predicted Functional Partners:
copZ
Putative copper chaperone - Cu2+-Cu+-Ag+-P-type ATPase.
  
 
 0.813
mntH
Metal ion (Mn2+-iron) transporter (Nramp) family protein; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.
  
 
 0.680
atpF
H+-translocating ATPase b subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
      
 0.513
ssrA
tmRNA-binding protein SsrA; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switc [...]
     
 0.488
stu0841
IS1191, transposase, IS256 family, truncated; Truncated.
       0.450
pacL1
Ca2+, Mn2+-P-type ATPase.
 
 
0.433
ctpE
Cation-P-type ATPase.
 
 
0.411
stu0351
Ca2+, Mn2+-P-type ATPase, truncated; Truncated.
 
 
 0.402
stu0932
Cation diffusion facilitor (CDF) family protein.
 
  
 0.400
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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