Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
adcAZinc (Zn2+) ABC uptake transporter substrate binding protein; Belongs to the bacterial solute-binding protein 9 family. (514 aa)    
Predicted Functional Partners:
adcC
Zinc (Zn2+) ABC uptake transporter ATP-binding protein.
 
 
 0.999
adcB
Zinc (Zn2+) ABC uptake transporter membrane-spanning protein.
 
 
 0.999
adcR
Zinc transport transcriptional repressor.
  
  
 0.998
purL
Phosphoribosylformylglycinamidine synthase II (FGAM synthetase).
     
 0.944
rpsN
30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
  
  
 0.888
ecfA1
ABC transporter ATP binding protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity). Expression of the complex plus RibU in de-energized E.coli allows riboflavin uptake.
     
 0.734
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
     
 0.710
argH
Argininosuccinate lyase.
      
 0.707
argG
Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
     
 0.706
rpmE
50S ribosomal protein L31.
  
  
 0.694
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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