Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
stu0888Conserved hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. (110 aa)    
Predicted Functional Partners:
ffh
Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
  
 0.994
whiA
Conserved hypothetical protein; Involved in cell division and chromosome segregation.
  
  
 0.840
stu0887
Transcription regulator GntR family.
       0.743
stu1249
Conserved hypothetical protein.
  
     0.724
stu1739
Conserved hypothetical protein.
 
     0.700
stu1959
Conserved hypothetical protein; Belongs to the UPF0297 family.
 
     0.695
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
    0.673
stu0342
Conserved hypothetical protein.
  
    0.666
asp
Alkaline-shock protein.
 
   
 0.596
ctsR
Transcriptional regulator of class III stress genes (heat shock response); Belongs to the CtsR family.
  
     0.579
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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