STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hk04Sensor histidine kinase (homolog to spaK Bsu). (470 aa)    
Predicted Functional Partners:
rr04
Response regulator (homolog to spaR Bsu & DvnR Cdi).
 
 0.996
rr07
Response regulator (homolog to RR01Spn & Sth).
 
 
 0.813
stu1381
Response regulator (homolog to RR08 Spn) uncoupled, truncated; Truncated.
 
 
 0.795
rr05
Response regulator (homolog to RR02/MicA Spn & RR02 Sth &VicR Spy).
 
 
 0.793
rr01
Response regulator (homolog to csrR/covR Spy).
 
 
 0.790
stu0792
Response regulator (homolog to ciaR Spn), truncated; Truncated.
 
 
 0.731
stu0900
Conserved hypothetical, predicted membrane protein (TMS8).
 
     0.729
hk07
Sensor histidine kinase (homolog to HK01Spn & Sth).
 
 
 0.635
gid
Glucose-inhibited division protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily.
       0.524
tnpSth1-4
ISSth1, transposase (orf1), IS3 family.
       0.464
Your Current Organism:
Streptococcus thermophilus
NCBI taxonomy Id: 264199
Other names: S. thermophilus LMG 18311, Streptococcus thermophilus LMG 18311, Streptococcus thermophilus str. LMG 18311, Streptococcus thermophilus strain LMG 18311
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.