node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
carB | pyrB | stu0527 | stu0525 | Carbamoyl phosphate synthetase, large chain. | Aspartate transcarbamoylase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carB | pyrC | stu0527 | stu1054 | Carbamoyl phosphate synthetase, large chain. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.994 |
carB | pyrDa | stu0527 | stu1207 | Carbamoyl phosphate synthetase, large chain. | Dihydroorotate dehydrogenase A; Catalyzes the conversion of dihydroorotate to orotate. | 0.706 |
carB | pyrDb | stu0527 | stu0955 | Carbamoyl phosphate synthetase, large chain. | Dihydroorotate dehydrogenase B; Catalyzes the conversion of dihydroorotate to orotate. | 0.746 |
carB | pyrE | stu0527 | stu0968 | Carbamoyl phosphate synthetase, large chain. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.929 |
carB | pyrF | stu0527 | stu0967 | Carbamoyl phosphate synthetase, large chain. | orotidine-5-Phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.922 |
carB | pyrR | stu0527 | stu0523 | Carbamoyl phosphate synthetase, large chain. | Pyrimidine regulatory protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.823 |
carB | upp | stu0527 | stu0355 | Carbamoyl phosphate synthetase, large chain. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.466 |
pyrB | carB | stu0525 | stu0527 | Aspartate transcarbamoylase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Carbamoyl phosphate synthetase, large chain. | 0.999 |
pyrB | pyrC | stu0525 | stu1054 | Aspartate transcarbamoylase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.999 |
pyrB | pyrDa | stu0525 | stu1207 | Aspartate transcarbamoylase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Dihydroorotate dehydrogenase A; Catalyzes the conversion of dihydroorotate to orotate. | 0.759 |
pyrB | pyrDb | stu0525 | stu0955 | Aspartate transcarbamoylase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Dihydroorotate dehydrogenase B; Catalyzes the conversion of dihydroorotate to orotate. | 0.782 |
pyrB | pyrE | stu0525 | stu0968 | Aspartate transcarbamoylase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.944 |
pyrB | pyrF | stu0525 | stu0967 | Aspartate transcarbamoylase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | orotidine-5-Phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.962 |
pyrB | pyrH | stu0525 | stu0438 | Aspartate transcarbamoylase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.704 |
pyrB | pyrR | stu0525 | stu0523 | Aspartate transcarbamoylase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Pyrimidine regulatory protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.991 |
pyrB | upp | stu0525 | stu0355 | Aspartate transcarbamoylase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.622 |
pyrC | carB | stu1054 | stu0527 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Carbamoyl phosphate synthetase, large chain. | 0.994 |
pyrC | pyrB | stu1054 | stu0525 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Aspartate transcarbamoylase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
pyrC | pyrDa | stu1054 | stu1207 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Dihydroorotate dehydrogenase A; Catalyzes the conversion of dihydroorotate to orotate. | 0.973 |